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[MCE] New Small Molecules for May 2019

관리자 2019.05.14 15:43 조회 28

MedChemExpress-Master of Small Molecules (Inhibitors, Agonists, Screening Libraries)
MedChemExpress - New Products
MedChemExpress (MCE) offers a wide range of high quality research chemicals and biochemicals including novel bioactive compounds, dye reagents, peptides and natural compounds for laboratory and scientific use.
•  Over 10,000 bioactive molecules in stock •  High purity & competitive prices
•  Target 375 key proteins in 20 signaling pathways •  Data sheet with detailed biological information
•  Quality reports (LC/MS, NMR and HPLC) for each product •  Delivery within 24 hours
•  Release more than 100 of the newest biochemicals per month  
• Glucocorticoid Receptor Modulator
AZD9567

CAS No.: 1893415-00-3

AZD9567 (compound 15) is a potent, oral active, non-steroidal and selective glucocorticoid receptor modulator (SGRM), with an IC50 of 3.8 nM. Exhibits excellent efficacy in the streptococcal cell wall (SCW) reactivation model of joint inflammation.

• Calcium Channel Blocker
ACT-709478

CAS No.: 1838651-58-3

ACT-709478 is a potent, selective, orally active, and brain penetrating T-type calcium channel blocker. ACT-709478 is used in the research of generalized epilepsies.

• Melanocortin Receptor Agonist
β-Melanocyte Stimulating Hormone (MSH), human (TFA)

β-Melanocyte Stimulating Hormone (MSH), human (TFA) is a melanocortin (MC) receptor agonist.

• Opioid Receptor Antagonist
LY-2940094

CAS No.: 1307245-86-8

LY2940094 is a potent, selective and orally available nociceptin receptor (NOP) antagonist with a Ki of 0.105 nM.

• Parasite Inhibitor
Artemisone

CAS No.: 255730-18-8

Artemisone (Artemifone) is a potent and semi-synthetic antimalarial, inhibits P. falciparum strains, with a mean IC50 of 0.83 nM.

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Other New Products This Month

INH14 (IKK) | (-)-(S)-B-973B (nAChR) | A-381393 (Dopamine Receptor) |
USL311 (CXCR) | Rac-Nedisertib (DNA-PK) | JNJ-64619178 (Histone Methyltransferase) |
Abrocitinib (JAK) | SAR125844 (c-Met/HGFR) | CAY10471 Racemate (Prostaglandin Receptor) |
BTR-1 (Apoptosis) ...