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[alomone labs] Switching off to switch pacemaker cells on

관리자 2023.06.30 14:42 조회 618 추천 9
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Switching off to switch pacemaker cells on



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What if we could stop implanting pacemakers and create biological pacemakers by turning existing cardiomyocytes into specialized pacemaker cells? A US team of scientists have been doing just that, but along the way they discovered that for pacemaker cells to ‘switch on’, you first need to suppress some rebellious microRNAs.


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New Products


Membrane Protein Immunodetection


Primary Antibodies:


Guinea Pig Anti-5HT2A Receptor (HTR2A) (extracellular) Antibody

A Guinea Pig Polyclonal Antibody to 5-HT2A Receptor

Cat #: ASR-033-GP
Type: Polyclonal | Host: Guinea Pig | Applications: IHC, WB, *ICC, *IP |

Reactivity: H, M, R


A Rabbit Polyclonal Antibody to Apelin Receptor

Cat #: AAR-030

Type: Polyclonal | Host: Rabbit | Applications: IF, IFC, IHC, WB, *ICC, *IP, *LCI | Reactivity: H, M, R



Antibodies for Live Cell Direct Flow Cytometry:

Anti-β2-Adrenergic Receptor (extracellular)-FITC Antibody

A Rabbit Polyclonal Antibody to β2-Adrenergic Receptor Conjugated to the Fluorescent Dye FITC

Cat #: AAR-016-F
Type: Polyclonal | Host: Rabbit | Applications: FC, LCI *ICC |

Reactivity: H, M, R

Anti-α1B-Adrenergic Receptor (extracellular)-ATTO Fluor-488 Antibody

A Rabbit Polyclonal Antibody to α1B-Adrenergic Receptor Conjugated to the Fluorescent Dye ATTO-488

Cat #: AAR-018-AG
Type: Polyclonal | Host: Rabbit | Applications: FC, ICC, IF, LCI, *IHC |

Reactivity: H, R




Ion Channel Pharmacology

Venom Toxins:

ω-Conotoxin FVIA

A Potent Blocker of CaV2.2 Channel

Cat #: STC-780
Type: Toxins | SourceNatural peptide | MW: 2567 Da |

Target: CaV2.2 channels

Aam-KTX

A Blocker of Voltage-Gated K+ channels

Cat #: STA-110
Type: Toxins | SourceSynthetic peptide | MW: 4185 Da |

Target: KV K+ channels

 

Why Alomone Labs?

Because we've been producing and validating membrane protein molecular tools in-house for decades.




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