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[Intact Genomics] CRISPR Genome Editing via Prime Editing

관리자 2023.11.01 13:29 조회 471 추천 0
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CRISPR Genome Editing via Prime Editing




Unlock Precision Genome Editing with PEmax Enzyme –

Your Prime Choice for CRISPR Editing!



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We are excited to launch a unique addition to our CRISPR lineup:

IG® pegRNA Synthesis Kit and PEmax Enzyme.




Now Available! IG® is proud to launch two new products: IG® pegRNA Synthesis Kit, an easier way to achieve higher yields of pegRNA for CRISPR prime-editing and PEmax Enzyme, a fusion protein of the SpCas9 nickase mutant (H840A) and a Murine Moloney Leukemia Virus-Reverse Transcriptase.



Together, the products enable a search-and-replace strategy of precision genome editing. PEmax Enzyme uses the pegRNA to target the DNA edit site, which also provides the template for nucleotide changes.  



To find out more about these novel products, check out our website!




Products

Product Links


Size Available


Application & Benefits


Cas9 Nuclease

80µg & 400µg

Purified recombinant Streptococcus pyogenes Cas9 enzyme containing a nuclear localization signal (NLS).

Cas12a Nuclease

80µg & 400µg

Intact Genomics Cas12a Nuclease Cas12a Nuclease is the purified recombinant Streptococcus pyogenes Cas12a enzyme for in vitro editing

PEmax Enzyme

80µg & 400µg

IG® PEmax enzyme is the purified recombinant Streptococcus pyogenes Cas9 nickase mutant (H840A)-MMLV-Reverse Transcriptase fusion protein containing a NLS

sgRNA Synthesis Kit for Cas9 Nuclease

10 Reactions

With high and scalable yield, the IG® sgRNA Synthesis Kit for Cas9 nuclease is the perfect choice for a variety of sgRNA synthesis needs.

sgRNA Synthesis Kit for Cas12a Nuclease

10 Reactions

High and scalable yield, the IG® sgRNA Synthesis Kit for Cas12a nuclease is the perfect choice for a variety of sgRNA synthesis needs.

PE pegRNA Synthesis Kit

10 Reactions

The IG® PE pegRNA synthesis kit is simple to use, and is scalable to help you reach necessary yields of pegRNA

RNA Cleanup Kit

25 Preps & 100 Preps

The IG® RNA Cleanup Kit purifies and concentrates up to 50 µg of RNA from enzymatic reactions.

T7 RNA Polymerase

5,000U & 25,000U

T7 RNA Polymerase is useful for sgRNA and mRNA synthesis, RNA synthesis from DNA templates and applications in mRNA therapeutics



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